GCRC Number IRB Number Title P.I.
1363HS-10-002673C-10-1 A Dose Finding and Phase II Study of AZD6244 (Hyd-Sulfate) in Combination with Irinotecan in 2nd Line Patients with K-ras or B-raf Mutation Positive Advanced or Metastatic Colorectal CancerLenz, Heinz-Josef
1361HS-10-000764B-09-1-An Open-label, Single-arm, Phase II Trial of Intravenous BI 6727 in Patients with Locally Advanced, Metastatic or Recurrent Urothelial Cancer of the Bladder, Renal Pelvis, or Ureters After Failure of Prior ChemotherapyQuinn, David
1360HS-10-002153C-10-2-A Phase 1/2 Study of BMS-908662 (XL281) Alone or in Combination with Cetuximab in Subjects with K-RAS or B-RAF Mutation Positive Advanced or Metastatic Colorectal CancerLenz, Heinz-Josef
1358HS-10-002294P-10-1 An Open-label Phase 1 / 2 Study of TAK-700 in Combination with Docetaxel and Prednisone in Men with Metastatic Castration-Resistant Prostate CancerAgus, David
1357HS-10-00042Protocol H8A-MC-LZAN. Effect of Passive Immunization on the Progression of Alzheimer's Disease: Solanezumab (LY2062430) versus PlaceboSchneider, Lon
1356HS-10-002553G-10-2-A Randomized, Open-Label, Multi-Center Phase II Study to Compare AUY922 with Docetaxel or Irinotecan in Adult Patients with Advanced Gastric Cancer, who have Progressed after One Line of ChemotherapyIqbal, Syma
1355HS-09-00636A phase II, randomized, double-blind, placebo-controlled dose-ranging study to evaluate Lebrikizumab (MILR1444A) in adult patients with asthma who are not taking inhaled corticosteroids (MOLLY)Barbers, Richard
1354HS-09-00602A long-term, open-label follow-up study of CP-690,550, a moderately selective Janus-Kinase-3 inhibitor, for treatment of rheumatoid arthritisStohl, William
1353HS-10-00119Phase 3 randomized, double-blind study of the efficacy and safety of doses of CP-690,550 compared to Methotrexate in Methotrexate-naive patients with rheumatoid arthritisStohl, William
1352HS-09-00624Randomized, double-blind, placebo-controlled study of the effect of a single injection of SAR164877 (REGN475) on reduction of pain from vertebral fracture associated with osteoporosisHsieh, Patrick
1351HS-10-000726G-09-1-Cilengitide for Subjects with newly Diagnosed Glioblastoma Multiforme and Methylated MGMT Gene Promoter – a Multicenter, Open-label, Controlled Phase III Study, Testing Cilengitide in Combination with Standard Treatment (Temozolomide with Concomitant Radiation Therapy, Followed by Temozolomide Maintenance Therapy) versus Standard Treatment Alone (CENTRIC)Chen, Thomas
1350HS-10-001170C-09-8, A Phase 1 Open-Label, Dose-Escalation Study of Veliparib in Combination with Bimonthly FOLFIRI in Subjects with Advanced Solid Tumors [M10-977]Lenz, Heinz-Josef
1349HS-10-001740C-10-1,An Open-Label, Phase I, Dose-Escalation Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0623 Administered Daily in Patients with Locally Advanced or Metastatic Solid TumorsEl-Khoueiry, Anthony
1348HS-10-00080OC-09-7-A Phase 1/2 Study of the Combination of RDEA119 and Sorafenib in Patients with Advanced CancerEl-Khoueiry, Anthony
1346HS-10-001034T-09-1-Multicenter Phase 2 Trial of ARQ 197 for Subjects with Relapsed or Refractory Germ Cell TumorsQuinn, David
1345HS-10-001051B-10-1-A Phase 1-2 and Pharmacologic Study of MM-111 in Patients with Advanced, Refractory Her2 Positive CancersGarcia, Agustin
1340HS-09-00582Phase 3 Double-Blind, Placebo-Controlled Study Of The Efficacy And Safety Of 2 Doses of CP-690,550 In Subjects With Rheumatoid Arthritis On Background Methotrexate Who Have Had Inadequate Response To Prior TNF Inhibitor TherapyStohl, William
1338HS-09-00559Type 2 Diabetes in Hispanic Adolescents (Study of Latinos at Risk II -SOLAR II)Goran, Michael
1337HS-09-006973G-09-4-A Phase Ib Multiple Ascending Dose Study to Evaluate the Safety of Brivanib in Combination with 5-Fluorouracil/Leucovorin (5FU/LV) and Brivanib in Combination with 5-Fluorouracil/Leucovorin/irinotecan (FOLFIRI) in Subjects with Advanced or Metastatic Gastrointestinal MalignanciesEl-Khoueiry, Anthony
1334HS-09-0024513NHL-09-2: PhI-58 Phase I Study of GX15-070 (NSC # 729280) and Bortezomib in Aggressive Relapsed/Recurrent Non-Hodgkin's LymphomaAilawadhi, Sikander
1332HS-09-00313Validation of the Biospace Bioelectrical Impedance Body Composition Analyzers with Deuterium Water StudiesSchroeder, Todd
1331HS-09-005762N-09-1-A Phase III, Randomized, Double-blind, Placebo-controlled Multi-center Study of ASA404 in Combination with Docetaxel in second-line Treatment of Patients with Advanced or Metastatic (Stage IIIb/IV) Non-small Cell Lung Cancer (NSCLC)Gitlitz, Barbara
1330HS-09-00330Comparison of Monthly Pulse ACTH (Acthar Gel) Therapy with Methylprednisolone (MP, Solumedrol) for Long-Term Treatment of Multiple Sclerosis (MS) as an Add on Therapy to Beta-interferons (Avonex, Betaseron or Rebif)Berkovich, Regina
1328HS-09-00307Predictors of Bisphosphonate Related Osteonecrosis of the Jaw: A Pilot StudyLe, Anh
1327HS-09-004894A-09-1-A Randomized, Double-blind, Placebo-controlled, Phase 3 Study of OSI-906 in Patients with Locally Advanced or Metastatic Adrenocortical CarcinomaQuinn, David
1326HS-09-00327Effects of Resistance Training and Creatine/Protein Supplementation on Muscle Mass, Strength, and Performance in Older MenVillanueva, Matthew
1325HS-09-00281Drug-Induced Liver Injury Network (DILIN) Idiosyncratic Liver Injury Associated with Drugs (ILIAD):A Retrospective StudyStolz, Andrew
1323HS-09-004220C-09-4-An Open-label Phase II trial of BIBW 2992 in Genetically Pre-Screened Cancers with EGFR and/or HER2 gene Amplification or EFGR Activating MutationsLenz, Heinz-Josef
1322HS-04A056Causes of Germ Cell Tumors and Related ConditionsCortessis, Victoria
1321HS-09-003903G-09-1-Phase 1b Multiple Ascending Dose Study of BMS-833923 (XL139) Administered in Combination with Cisplatin and Capecitabine as First-Line Therapy in Patients with Inoperable Metastatic Gastric, Gastroesophageal, or Esophageal AdenocarcinomasEl-Khoueiry, Anthony
1319HS-09-00142A Randomized, Double-Blind, Placebo-Controlled, Two Dose-Arm, Parallel Study of the Safety and Effectiveness of Immune Globulin Intravenous (Human), 10% (IGIV, 10%) for the Treatment of Mild-To-Moderate Alzheimer's DiseaseSchneider, Lon
1318HS-08-00435Genomic Psychiatry Cohort: Schizophrenia Disorder StudyPato, Carlos
1317HS-08-00313Genomic Psychiatry Cohort: Bipolar Disorder Study (GPC: BPD)Pato, Carlos
1315HS-09-00246Influence of Genes and Emotions on Medication EffectsLeventhal, Adam
1314HS-08-00456AMC 059-A Phase 1/2 Trial of PTC-299 in Patients with HIV-Related Kaposi's SarcomaTulpule, Anil
1313HS-09-002360C-09-3, A Phase I, Multi-arm, Dose Escalation Study of Brivanib Alaninate Combined with Several Chemotherapy Regimens in Subjects with Advanced or Metastatic Solid Tumors (CA 182030)El-Khoueiry, Anthony
1312HS-09-002881B-09-7, A Phase 1/2, Open-label Study of Neratinib (HKI-272) in Combination with Capecitabine in Subjects with Solid Tumors and ErbB-2 Positive Metastatic or Locally Advanced Breast Cancer (3144A1-2206WW)Garcia, Agustin
1311HS-09-00016Brain reward as a link between insulin resistance and weight gain in Hispanic adolescentsAdam, Tanja C.
1309HS-09-00223Phl-63(0S-09-1) A Phase 1 Study of Chronically-Dosed, Single-Agent ABT-888 in Patients with Either BRCA 1/2-Mutated Cancer; Platinum-Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer; or Basal-Like Breast Cancer (NCI#8282 UPCl#08-121)Garcia, Agustin
1308HS-08-00662A5257: A Phase III Comparative Study of Three Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)-Sparing Antiretroviral Regimns for Treatment-Naïve HIV-1-Infected VolunteersDube, Michael
1306HS-09-00139PHI-62 A Phase I Study of ABT-888 in Combination with Metronomic Cyclophosphamide in Adults with Refractory Solid Tumors and Lymphomas (0C-08-4)Lenz, Heinz-Josef
1305HS-08-00448(1B-07-3) A Phase III, Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of Pertuzumab + Trastuzumab + Docetaxel vs. Placebo + Trastuzumab + Docetaxel in Previously Untreated Her2-Positive Metastatic Breast CancerSpicer, Darcy
1303HS-09-00161A Phase II Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Parallel Evaluation of the Efficacy and Safety of K-604 by High-Resolution Magnetic Resonance Imaging (MRI) in carotid atherosclerotic PlaqueSanossian, Nerses
1302HS-09-00107Phase 1 Pharmacokinetics Study of Dasatinib (BMS-354825) (NSC-732517: IND-73969) in Patients with Advanced Malignancies and Varying Levels of Liver Dysfunction (SWOG-S0711)El-Khoueiry, Anthony
1301HS-08-00450Atherothrombosis Intervention Metabolic Syndrome with Low HDL/High Triglyceride and Impact on Global Health Outcomes (AIM-High)Colletti, Patrick
1299HS-08-00582A Multi-Center, Continuation Trial of Belimumab (HGS 1006, LymphoStat-Ba), a Fully Human Monoclonal Anti-BlyS Antibody, in Subjects with Systemic Lupus Erythematosus (SLE) who Completed the Phase 3 Protocol HGS1006-C1056 in the United StatesStohl, William
1298HS-07-00612A Randomised, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study To Evaluate The Efficacy and Safety of Two Doses of Ocrelizumab in Patients With WHO or ISN Class III or IV Nephritis Due To Systemic Lupus ErythematosusStohl, William
1297HS-09-00058A Phase 1b/ 2 Trial of AMG 479 or AMG 102 in Combination with Platinum-based Chemotherapy as First-Line Treatment for Extensive Stage Small Cell Lung Cancer (20060534) (2O-08-3)Gitlitz, Barbara
1292HS-08-00655A Multi-Center, Longitudinal Study of Drug and CAM-Induced Liver InjuryStolz, Andrew
1291HS-08-00575A Phase 2, Multicenter, Two-Tier Study of IMC-A12 in Combination with Depot Otreotide in Patients with Metastatic, Well-or Moderately-Differentitated Carcinoid or Islet Cell Carcinoma (0S-08-12)Iqbal, Syma
1288HS-08-00082An Open-Label, 12-Month Safety and Efficacy Study of Levodopa – Carbidopa Intestinal Gel in Levodopa-Responsive Subjects with Advanced Parkinson's Disease and Severe Motor- Fluctuations Despite Optimized Treatment with Available Parkinson’s Disease MedicationsLew, Mark
1285HS-08-00449A Phase I, Open-Label, Multi-center, Dose-escalation Study of the Safety, Tolerability, and Pharmacokinetics of GC33, a Recombinant Humanized Antibody to Glypican-3 Administered Weekly in Patients with Advanced or Metastatic Hepatocellular Carcinoma (HCC) (3L-08-1)Lenz, Heinz-Josef
1283HS-08-003854B-08-1, Randomized Study of LAROTAXEL + Cisplatin (LC) vs. Gemcitabine + Cisplatin (GC) in the First Line Treatment of Locally Advanced/Metastatic Urothelial Tract or Bladder Cancer (EFC6668)Quinn, David
1280HS-08-00270Genetics of Beta Cell Failure in Mexican Americasn - Phase IIBuchanan, Thomas
1279HS-08-00297Diabetes Risk due to Ectopic Adiposity in Minority YouthWeigensberg, Marc
1277HS-07-00735Food, Adolescence, Mood, and Exercise (FAME) StudySpruijt-Metz, Donna
1276HS-08-00254A Randomized, Double-Blind, Placebo Controlled, Cross-over Study of the Effectiveness of Immune Globulin Intravenous (Human), 10% (IGIV, 10%) for the Treatment of Multifocal Motor NeuropathyBeydoun, Said
1272HS-07-00696A randomized, double-blind, parallel group, international study to evaluate the safety and efficacy of ocrelizumab in combination with methotrexate (MTX) compared to MTX alone in methotrexate-naïve patients with active rheumatoid arthritisStohl, William
1270HS-07-00702A Phase 3, Randomized, Rater-and Dose-Blinded Study Comparing Two Annual Cycles of Intravenous Low- and High- Dose Alemtuzumab to Three-Times Weekly Subcutaneous Interferon Beta-1a(Rebif) in Patients with Relapsing-Remitting Multiple Sclerosis Who Have Replased On TherapyWeiner, Leslie
1268HS-08-001210C-07-9, Phl-60 A phase 1 and Pharmacokinetic Single Agent Study of Pazopanib in Patients with Advanced Malignancies and Varying Degrees of Liver Dysfunction (NCI #8063)Lenz, Heinz-Josef
1267HS-08-00038A Blinded, Randomized, Phase 1/2 Study of Brivanib Alaninate vs. Placebo in Combination with Erbitux and Irinotecan in Subjects with Metastatic Colorectal Cancer (3C-07-5)El-Khoueiry, Anthony
1264HS-07-00636Carotid Plaque Composition by MRI During Lipid-LoweringColletti, Patrick
1263HS-08-00029A Phase I Dose Escalation Study of MK-8033 in Patients with Advanced Solid Tumors (0C-07-5)Lenz, Heinz-Josef
1262HS-08-00001PhI-61 A Phase 1 Study of ABT-888 in Combination with Carboplatin and Paclitaxel in Advanced Solid Malignancies (0C-07-7)Lenz, Heinz-Josef
1261HS-07-00498A Randomized, double-blind, parallel group, international study to evaluate the safety and efficacy of ocrelizumab compared to placebo in patients with active rheumatoid arthritis who have inadequate response to at least one anti-TNF-a therapyStohl, William
1260HS-08-00017Effect of Doxycycline on Sputum Biomarkers of Inflammation and Lung Epithelial Repair in Patients with Cyctic FibrosisBeringer, Paul
1247HS-06-00415RED-HF StudyElkayam, Uri
1239HS-06-00421Pharmacogenetics of Diabetes PreventionWatanabe, Richard
1233HS-07-00406A Randomized, double-blind, parallel group, international study to evaluate the safety and efficacy of ocrelizumab compared to placebo in patients with active rheumatoid arthritis continuing methotrexate treatmentStohl, William
1229HS-06-00323Phase I Trial of 5-Fluoro-2'-Deoxycytidine with Tetrahydrouridine (0C-99-1)El-Khoueiry, Anthony
1228HS-07-00175A Pharmacokinetic Study of BMS-582664 in Subjects with Advanced Solid Malignancies and Normal Hepatic Function, and/or Hepatocellular Carinoma with Impaired Hepatic Function (0C-07-1)El-Khoueiry, Anthony
1221HS-07-00155PHI-53 A Phase 1 Trial of PXD101 in Combination with 13-cis-Retinoic Acid in Advanced Solid Tumor Malignancies (0C-05-5)Lenz, Heinz-Josef
1219HS-07-00126PHI-55 A Phase 1 Study of Halichondrin B Analog (E7389) in Combination with Cisplatin in Advanced Solid Tumor (0C-06-3)Lenz, Heinz-Josef
1201HS-06-00508A Phase 1/2a Study Evaluating the Safety, Pharmacokinetics and Efficacy of ABT-263 in Subjects with Relapsed or Refractory Lymphoid MaglignanciesTulpule, Anil
1198HS-06-00204Phil-75, A Phase I/II Study of E7389 Halichondrin B analog (NSC #707389; IND #64395) in Metastatic Urothelial Tract Cancer and Renal Insufficiency (4B-06-1)Quinn, David
1196HS-06-00179PHI-54 A Phase I Study of IV Fenretinide in Patients with Malignant Solid Tumors (OC-05-8)Pinski, Jacek
1177HS-05-00432A Randomized, Phase 3, Controlled, Double-Blind, Parallel-Group, Multicenter Study to Evaluate the Safety and Efficacy of Rituximab in Combination with Methotrexate (MTX) Compared to MTX Alone, in Methotrexate-Naïve Patients with Active RAStohl, William
1157HS-057001A Multi-Center, Open-Label, Continuation Trial of LymphoStat-B Antibody (Monoclonal Anti-BlyS Antibody) in Subjects with Systemic Lupus Erythematosus (SLE) who Completed the Phase 2 Protocol LBSL02. Protocol #1074 ContinuationStohl, William
1156HS-055009Investigator Initiated Study of the Effects of Androgen Therapy on Carbohydrate and Lipid Metabolism in Elderly MenSattler, Fred
0956HS-007028Risk of Type II Diabetes in Hispanic AdolescentsGoran, Michael